Posts

Showing posts with the label Optic atrophy

An overview of Wolfram syndrome

  Wolfram syndrome is very rare and it comes under a group of genetic diseases. Wolfram syndrome is a progressive and neurodegenerative disorder which highly damages your brain and other tissues in the body. Usually, a sequence of symptoms will appear during the period of childhood to adulthood.Before the age of 15, first symptoms of this syndrome are diabetes and vision changes. And followed by impaired brain function which leads to early death. Types Healthcare professionals have to identify two genes which are involved in Wolfram syndrome disease. Typically genes are sequences of DNA which carries genetic information. People who have Wolfram syndrome must have changes in their genes. Healthcare professionals classified the Wolfram syndrome which is usually based on the affected genes: Wolfram syndrome type 1 -   mutation of the WFS1 gene. Wolfram syndrome type 2 - mutation of the WFS2 (CISD2) gene. How is Wolfram syndrome inherited? Wolfram syndrome will be passed on by the...