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Showing posts with the label cartilage tissues

Achondrogenesis | Osteochondrodysplasias | Skeletal dysplasia

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Achondrogenesis is generally described as rare skeletal dysplasia in which the patient will experience extreme shortening of the arms and legs when it is compared to the trunk, ribs, vertebrae, and overall skeletal. And this disorder is also called osteochondrodysplasias. Because of the characteristics of this disorder it will be extremely life-threatening to the people, especially during their infancy stage as the newborns will die shortly because of respiratory failure. Types of Achondrogenesis are: Achondrogenesis type IA (Houston-Harris type). Achondrogenesis type IB (Fraccaro type). Achondrogenesis type II (Langer-Saldino type). Type IA and type IB of Achondrogenesis are autosomal recessive. And Achondrogenesis type II autosomal dominant disorder makes all other types different from each other types. But three types of Achondrogenesis are usually identified by prenatal ultrasound examination within 14-17 weeks of gestational age. Causes Each type of Achondrogenesis is different fr...

Achondroplasia | Genetic disorder | Bone Growth Disorder

  Achondroplasia is generally described as a bone development disorder which results in dwarfism because of genetic or gene mutation in the arms and legs of your body. Achondroplasia comes under the form of short stature which means adults less than 4-ft. 10-in. in height. But almost all children who are affected with achondroplasia are able to live full and healthy lives after the diagnosis of disease. In the early stages of fetal development, most of the fetal skeleton is mainly made up of cartilage tissue, which eventually turns into bone. Achondroplasia happens when the cartilage tissues do not develop complete bone development of your arms and legs. This genetic disorder leads to short-limb dwarfism with the upper parts of arms and legs being shorter than the lower portions of those limbs which means rhizomelic shortening. Causes Generally, achondroplasia disorder is typically caused by a mutated gene which is in the receiver that converts cartilage tissues to bone development...